Visible Light-Activated PhotoCORMs
نویسندگان
چکیده
منابع مشابه
Visible Light-Activated PhotoCORMs
Despite its well-known toxicity, carbon monoxide (CO) is now recognized as a potential therapeutic agent. Its inherent toxicity, however, has limited clinical applications because uncontrolled inhalation of the gas leads to severe systemic derangements in higher organisms. In order to obviate life-threatening effects and administer the gas by bypassing the respiratory system, CO releasing molec...
متن کاملPhotoCORMs: CO release moves into the visible.
The potential of carbon monoxide to act as a therapeutic agent is now well-established. Controlled delivery of CO is best achieved using 'CORMs': molecules which release known amounts of carbon monoxide in response to a stimulus. Metal carbonyl complexes will release CO if irradiated with ultraviolet light, but it is only in the past five years that development of true 'photoCORMs' has been exp...
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The relationships between the transmission coefficient and the cure depth were evaluated on eight commercially available light-activated resin composites. The determination of transmission coefficient was carried out by the use of a radiometer for various shades of the resin composites. The transmission coefficient, ranging from 0.042 to 0.263, wasdependent upon the shade of the resin. There wa...
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متن کاملVisible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores.
Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.
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ژورنال
عنوان ژورنال: Inorganics
سال: 2017
ISSN: 2304-6740
DOI: 10.3390/inorganics5020024